一：个人简介

2024-至今，英国上市365，讲师

2021-2023，山东大学，博士后

2016-2021，英国上市公司365，博士

2012-2016，英国上市公司365，学士

E-mail：623056@sdnu.edu.cn

办公地点：英国上市365博物楼A座531

二：主要研究方向

细胞骨架是一种高度动态的结构体系，对细胞的结构和功能发挥组织作用，并进一步影响细胞的形态、运动以及周围的细胞和环境，与人类疾病密切相关。主要的研究方向：（1）关注微管组织中心—中心体在组织器官发育和个体稳态的作用；（2）关注微管和动力蛋白组成的高度特化结构纤毛的发生和解聚，探究蛋白互作、蛋白修饰等发挥的调控机制，为纤毛病的诊治提供新依据。

关键词：微管、中心体、纤毛、组织器官发育、纤毛相关疾病

三：主持的科研项目

国家自然科学基金青年项目：去乙酰化酶HDAC6调控角膜上皮发育的分子机制，2024/01-2026/12，30万元，在研，主持。

山东省自然科学基金青年项目：哺乳动物动纤毛中央微管组装的机制研究，2025/01-2027/12，12万元，在研，主持。

四：代表性论文及论著

1. Ting Song*, Qingchao Li*, Qian Lyu*, Junkui Zhao*, Xirui Zi, Shuxiang Ma, Jiajun Luo, Shushen Li, Shanshan Nai, Hongbin Liu, Xueliang Zhu, Te Li, Jun Zhou^#, Huijie Zhao^#. EFCAB10 anchors AK8 to the radial spoke for proper ciliary motility. Proc Natl Acad Sci USA (in press).

2. Ting Song*, Xueqing Han, Hanxiao Yin, Junkui Zhao, Mingming Ma, Xiaonuan Wen, Chunli Liu, Yiyang Yue, Huijie Zhao, Jun Zhou, Yang Yang^#, Jie Ran^#, Min Liu^#. HDAC6 deacetylates ENKD1 to regulate mitotic spindle behavior and corneal epithelial homeostasis. EMBO Rep. 2025 May, 26(10):2597-2621. doi: 10.1038/s44319-025-00438-0.

3. Yue Lu*, Xirui Zi*, Qian Lyu*, Qingchao Li, Hanxiao Yin, Yinghao Wang, Qijun Chen, Bingkun Kang, Shanshan Nai, Jun Zhou, Huijie Zhao^#, Ting Song^#. Intraflagellar transport-associated CCDC92 is required for spermiogenesis and male fertility in mice. J Mol Cell Biol, 2025, mjaf022. doi: 10.1093/jmcb/mjaf022.

4. Ting Song*, Peng Zhou*, Fengguo Zhang*, Chunli Liu*, Xueqing Han, Yiyang Yue, Mingzheng Hu, Shaodong Yan, Qingchao Li, Min Liu, Jun Zhou^#, Huijie Zhao^#. USP21 deubiquitinates DPYSL2 and enhances its centrosomal abundance to promote cilium formation. J Genet Genomics, 2025, 4:S1673-8527(25)00193-6. doi: 10.1016/j.jgg.2025.06.006.

5. Qian Lyu*, Mingming Ma*, Ting Song^#. The Role of Microfilaments in Cilia Formation and Function. Cytoskeleton (Hoboken). 2025 Jul 31. doi: 10.1002/cm.70018.

6. Ting Song*, Yunfan Yang*, Peng Zhou, Jie Ran, Liang Zhang, Xiaofan Wu, Wei Xie, Tao Zhong, Hongbin Liu, Min Liu, Dengwen Li, Huijie Zhao^#, Jun Zhou^#. ENKD1 promotes CP110 removal through competing with CEP97 to initiate ciliogenesis. EMBO Rep. 2022 May 4;23(5):e54090. doi: 10.15252/embr.202154090.

7. Ting Song*, Na He, Ziqian Hao^#, Yunfan Yang^#. Upregulation of ENKD1 disrupts cellular homeostasis to promote lymphoma development. J Cell Physiol. 2023 Jun;238(6):1308-1323. doi: 10.1002/jcp.31012.

8. Ting Song*, Jun Zhou^#. Primary cilia in corneal development and disease. Zool Res. 2020 Sep 18;41(5):495-502. doi: 10.24272/j.issn.2095-8137.2020.109.

9. Ting Song*, Peng Zhou, Chunjiao Sun, Na He, Haixia Li, Jie Ran, Jun Zhou, Yue Wu^#, Min Liu^#. Enkurin domain containing 1 (ENKD1) regulates the proliferation, migration and invasion of non-small cell lung cancer cells. Asia Pac J Clin Oncol. 2022 Apr;18(2):e39-e45. doi: 10.1111/ajco.13550.